From the "Amerigo Vespucci" airport
A shuttle bus leaves every 30 minutes and takes you directly in front of Santa Maria Novella Station. From there you can take bus No. 23 A direction SORGANE and get off at the ORSINI stop and go back 30 meters on the same side. Or take the electric bus D direction Piazza Ferrucci. Get off at Piazza Ferrucci , walk across the square and enter Via G. Paolo Orsini, The B&B is the first doorway on the right after the bar.